educational Seminars
Dr. Goodenowe has over 30 years of diverse scientific research experience and has explored topics ranging from software, to mechanics, to theoretical physics, to neuroscience. From this vast knowledge, he creates regular presentations and videos exploring many topics of great interest to him and shares what he has learned. Each seminar has a written article and a video. These seminar videos contain relevant literature excerpts and detailed explanations. The written articles are posted below. To access the FREE seminars with full presentations and videos please visit Dr. Goodenowe’s resource site here. Once you are registered, you will be notified when new content becomes available.
Educational Seminar Updates
Lectures 4, 5, and 6 – Cognitive Impairment and the True Cause of Alzheimer’s Neuropathology: Breaking Alzheimer’s – The Definitive Lecture Series
Part I – Beware of what appears to be logically obvious A lot of things in our world appear obvious only to be proven wrong
Lecture 3 – The Biochemistry of Cognition: Breaking Alzheimer’s – The Definitive Lecture Series
I am the first and only scientist to solve the biochemical mechanism and cause of reduced cognition – a deficiency of plasmalogens in the synaptic membrane of cholinergic neurons leads to a reduced uptake of choline following
Lecture 2 – Philosophical Underpinnings: Breaking Alzheimer’s – The Definitive Lecture Series
The first step in the Breaking Alzheimer’s journey is to understand the differences between health and disease, life and death, and average lifespan versus maximum
Lecture 7 – APOE: Breaking Alzheimer’s – The Definitive Lecture Series
About one in four persons have a genetic predisposition for Alzheimer’s disease and dementia caused by having one or two copies of the ɛ4 allele of
Lecture 1 – Introduction: Breaking Alzheimer’s – The Definitive Lecture Series
Throughout most of human history, senile dementia (which occurs after age 65) has been considered a natural part of the aging process. It was not
ProdromeNeuro™ Improves Oxidative Stress Biomarkers in Cognitively Impaired Persons (C106)
Supplementation with ProdromeNeuro was observed to elevate blood DHA-plasmalogen levels. The increase in blood DHA-plasmalogens correlated with a decrease in malondialdehyde levels (r=-0.5, p=7.2e-07) and an increase in catalase activity (r=0.28, p=0.008). Superoxide dismutase
ProdromeNeuro™ Improves Cognition and Mobility in Cognitively Impaired Persons (C105)
Supplementation with ProdromeNeuro was observed to elevate DHA-plasmalogens in a dose-dependent manner and to improve cognition (p=1.8e-02) and mobility (p=2.9e-05) in persons diagnosed with mild to moderate dementia. To access the FREE seminars with full presentations and videos
Plasmalogen Supplementation Prevents Demyelination (C104)
Animals pretreated with plasmalogen supplements are protected against the neurotoxin cuprizone. Cuprizone selectively targets oligodendrocytes and creates symptoms and neuropathology similar to multiple sclerosis. To access the FREE seminars with full
Plasmalogen Supplementation Prevents Neurodegeneration (C103)
Animals pretreated with plasmalogen supplements are protected against the neurotoxin MPTP. MPTP selectively targets dopamine neurons and creates symptoms and neuropathology similar to Parkinson’s disease. To access the FREE
The Three Main Functions of Plasmalogens (C102)
Plasmalogens neutralize peroxides, they modulate membrane structure and the function of membrane proteins, and they modulate the efficiency and ease of vesicular release of neurotransmitters. They are obligate to life. To access the FREE
Plasmalogen Precursor Design and Development (C101)
Dr. Goodenowe was the first to discover and patent that low blood plasmalogens caused Alzheimer’s and he was the first to design and patent plasmalogen supplements that are effective neuroprotectants. To access the FREE seminars with
Uric Acid (B112)
Low blood uric acid levels are observed in neurological diseases such as Alzheimer’s disease, Parkinson’s disease, ALS, multiple sclerosis, schizophrenia, and central nervous system viral
Creatinine and Blood Urea Nitrogen (B111)
Low blood creatinine is associated with liver dysfunction, muscle wasting, and sarcopenia whereas high blood creatinine is associated with kidney disease. Creatinine is a metabolic product of creatine phosphate which is
Total, HDL, and LDL Cholesterol (B110)
Maintaining healthy circulating cholesterol levels is essential for optimal health. Low cholesterol levels are indicative of impaired liver or peripheral cell health and is associated with increased mortality.
Fasting Triglycerides and Peroxisomal Function (B109)
Maintaining low fasting triglycerides is essential to optimal health. High fasting triglycerides are indicative of mitochondrial or peroxisomal impairment, the two organelles responsible for fatty acid metabolism
Fatty Acid Elongase (B108)
Women diagnosed with active breast cancer or ovarian cancer have elevated fatty acid elongase activity. Abnormal cell growth (i.e., cancer) results in the activation of certain elongase enzymes which are used to
High Sensitivity C-Reactive Protein (B107)
C-Reactive Protein (CRP) is a non-specific biomarker of systemic inflammation. High blood CRP levels are associated with numerous diseases and increased risk of all-cause mortality and disease-specific mortalities. There are
Mitochondrial Stress and Leakage (B106)
Mitochondria are the most important organelle in the human body. Life cannot exist without functioning mitochondria. The key function of the mitochondria is to convert the stored chemical energy
Homocysteine and Methyltransferase Capacity (B105)
High homocysteine levels are associated with an increased risk of dementia, metabolic syndrome, and all-cause mortality. Homocysteine is a biomarker of methyltransferase activity and function. To access the FREE seminars with full presentations
Total Iron (B104)
Approximately 30% of the population are mildly anemic. Optimal iron levels are associated with healthy mitochondrial and peroxisomal function as well as a decreased risk
Gastrointestinal Tract Acids (GTAs) (B103)
Persons deficient in GTAs have been shown to have an increased risk of colorectal cancer and pancreatic cancer and other inflammatory diseases. GTAs are ultra-long chain
Dietary Fatty Acids (B102)
Dietary fatty acids are a critical source of energy, but their relative compositions in the phospholipids in the membranes of our body is where they exert their functional biological purpose. Low membrane
Plasmalogens and Phospholipids (B101)
Plasmalogens are required for proper membrane and nerve function and are found in high concentrations in the brain, heart, kidneys, lungs, and eyes. Low levels are
Metabolomics – Your Life and Death is Written in Your Blood (B100)
In 1999, I invented an advanced mass spectrometry technology platform that could simultaneously measure thousands of small molecules called metabolites, or biochemicals, in biological samples like human blood. I used this technology to
The False Hope and False Logic of Genes, Diseases, and Immortality (A106)
There will be no effective gene-based solutions to disease or immortality. I will explain using logic and science. As mentioned in the previous seminars in this
The Biochemistry of Death (A105)
In the end, mitochondrial failure is the source of all death – either directly or indirectly. The cells of the body are electrochemical in nature.
The Biochemistry of Life (A104)
There are so many things about human life that we take for granted. For example, most people do not know that the engine that runs
Living and Working in Reality – Using Classical Physics and Thermodynamics to Achieve Immortality (A103)
Whereas the brain is the physical and quantum mechanics is the theoretical components necessary to maintain consciousness and choice making, cellular chemistry is the physical
Duality and Choice-Making – the Brain and the Essence of Existence (A102)
Since the beginning of time, man has struggled to understand the nature of existence. All the world’s religions and philosophies have explanations for the conundrum
Are you focused on preventing death or preserving life? (A101)
The first step in the journey to understand immortality is to understand the differences between health and disease, life and death, and average lifespan versus
Plasmalogen Augmentation
Unfortunately, a person can take all of the necessary preventative measures such as diet, exercise, and maintaining a healthy liver function, and still have a
Plasmalogens and Alzheimer’s
Are you ready to make an investment in your health? Recently, I introduced you to plasmalogens and the role they play in optimizing health. Today,
Reaping the Benefits of Plasmalogens
We have all heard the phrase, “If it ain’t broke, don’t fix it”. This advice is valid for things that cause minimal inconvenience when they
ProdromeScan: The Gateway Technology
How valuable would a few more years of life be to you? What if you knew what was going to happen before it happened? What
My Journey of Discovery
My Journey of Discovery I have spent the last 30 years of my scientific career focused on diseases. Specifically, on understanding the biochemical mechanisms of
Redefining the Concept of Aging
Humans, as a whole, are obsessed with death; our death. We are also obsessed with time. Everything must have a beginning and an end, just
videos
The ProdromeScan Blood Test - What Does it Measure?
Plasmalogen Supplementation
What is a Plasmalogen?
Plasmalogen and Cognition
Scientific Evidence Linking Low Brain Plasmalogen Levels to Alzheimers Disease and Dementia
What is ProdromeNeuro Plasmalogen Oil?
Low Plasmalogens and Aging Dementia and Mortality The Scientific Evidence
Biochemical Mechanisms of Plasmalogens
The Scientific Evidence Linking Low Blood Plasmalogen Levels To Alzheimers Disease and Dementia
Prodrome Sciences Introduction
Death Disease Vitality and Immortality
What is Aging
What is a Prodrome?
How Plasmalogens Are Made and Why People Become Deficient with Age
How to Elevate Blood Plasmalogen Levels
